Trinucleotide Diseases and Instability O.P 2Teilzeitmodelle18

2Teilzeitmodelle18

Poster presenters were given the additional opportunity to summarize their papers in three minute spotlight presentations

Verzeichnis der AbbildungenIII

with each volume further broken down into two sections

Ellbogengesellschaft

Trinucleotide Diseases and Instability O.P 2Teilzeitmodelle18Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 such disease genes have been identified. All dynamic